CD27-PE Conjugated Antibody

B96790

List Price - 526.30


The CD27 molecule is a transmembrane disulfide-linked homodimer which belongs to tumor necrosis factor receptor (TNFR) / nerve growth factor receptor (NGFR) family. The molecular weight of the recognized antigen is 55 kDa / 120 kDa under reducing / non reducing conditions respectively. The CD27 glycoprotein is found on medullary thymocytes, peripheral T cells, subset of mature B cells and NK cells. On T cells, CD27 is preferentially expressed on the CD45RA+ CD45RO- naive subset of CD4+ T lymphocytes whereas most memory T cells (CD45RA- CD45RO+) lack CD27. Activation of T cells, when involving CD27 molecule, results in the upregulation of CD27 expression as cell surface embedded, and also in the release of a soluble form of CD27 (sCD27). CD70 antigen, which is a member of the TNF ligand superfamily, interacts with CD27 molecule and is known to be the CD27-ligand.

Caractéristiques

Target Species Human
Specificity CD27
Other Names T14, S152
Fluorochrome PE
Regulatory Status CE
Size 100 Tests
Format Liquid
Flow Product Line IOTest
Clone 1A4CD27
Isotype IgG1 Mouse
Cross Reactivity Cynomolgus Monkey, Indian Rhesus, Olive Baboon

Technical Documents

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