IL-4-PC7

B90441

List Price - 317.40


Interleukin-4 (IL-4) is a monomeric 20 kDa predominantly produced by activated T lymphocytes of the Th2 phenotype, by mast cells and by some antigen-presenting cells. Together with IL-2, IL-4 is an autocrine growth factor for activated T cells and for cytotoxic T cell precursors. IL-4 is a major factor involved in the activation of resting B lymphocytes. Together with IL-13, IL-4 induces isotype switch towards IgE and IgG1 isotypes. Activated CD4+ T cells of the Th1 phenotype produce predominantly IL-2 and Interferon γ, whereas CD4+ T cells of the Th2 phenotype produce IL-4, IL-5, IL6 and IL-10.

Caractéristiques

Target Species Human
Specificity IL-4
Other Names IL-4, interleukin-4
Fluorochrome PC7
Regulatory Status ASR
Size 0.5 mL
Format Liquid
Flow Product Line IOTest
Clone MP4-25D2
Isotype IgG1 Rat
Cross Reactivity Equine, Porcine

Technical Documents

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