TCR Vα24-PE

IM2283

List Price - 487.70


Also called TCRAV24S1 (according to the nomenclature from Arden et al.) Vα24 is the only described member of the subfamily of the T cell receptor. It has been shown to be expanded in a clonal fashion in the CD3+ CD8- CD4- cell population in PBL of several donors. It is expressed by 0.4% to 1% of peripheral CD3+ cells from normal blood. An invariant Vα24/Vβ11 T cell receptor is expressed in all individuals by clonally expanded CD4– CD8– T cells, reactive to bacterial antigens. This unique lymphocyte population restricted by the CD1d molecule recognition has been identified as the natural killer T (NKT) cells. The IGRa02 sequence is also referred to as TRAV10 (based on the IMGT gene nomenclature).

Caractéristiques

Target Species Human
Specificity TCR Vα24
Fluorochrome PE
Regulatory Status ASR
Size 1 mL
Format Liquid
Flow Product Line IOTest
Clone C15
Isotype IgG1 Mouse
Clone Description The C15 antibody recognizes the IGRa02 sequence, the only described member of this family.

Technical Documents

TOUS LES PRODUITS NE SONT PAS DISPONIBLES DANS TOUS LES PAYS
LA DISPONIBILITE DU PRODUIT ET LE STATUT REGLEMENTAIRE DEPENDENT DE L’ENREGISTREMENT SELON LE REGLEMENT APPLICABLE PAR PAYS