CD11b-APC

A87782

List Price - 231.90


The CD11b antigen is also known as the integrin αM subunit. It combines with the CD18 antigen (integrin β2 subunit) to build the integrin Mac-1 (CD11b/CD18, αMβ2, CR3, iC3bR, Mo-1). CD11b is a type I transmembrane glycoprotein of 170 or 165 kDa under reducing or non-reducing conditions, respectively. CD11b shows 19 potential N-glycosylation sites. Expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen (also known as β2 integrin chain). Together, these two subunits create the CD11b/CD18 integrin, one of the four integrin heterodimers that can be built by the association of CD18 β chain with four distinctive CD11 α chains. CD11b/CD18 is highly expressed on NK Cells, neutrophils, monocytes and macrophages.

Caractéristiques

Target Species Human
Specificity CD11b
Other Names alpha-chain of C3bi receptor, alphaM, C3bi receptor, CD11b, gp155/95, integrin a;M-chain, Mac-1
Fluorochrome APC
Regulatory Status ASR
Size 0.5 mL
Format Liquid
Flow Product Line IOTest
Clone Bear1
Isotype IgG1 Mouse
Clone Description Bear1 is a non blocking monoclonal antibody.

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