CD3 Unlabeled Antibody

IM1304

List Price - 272.10


CD3ζ see TCRζ in Human non-CD antigens section. The CD3 antigen is a complex of 5 invariable polypeptidic chains, γ, δ, ε, ζ and η, whose molecular weights are respectively 25-28, 21, 20, 16 and 22 kDa. The ζ chain occurs in the CD3 complex as a disulphide linked homodimer or as a heterodimer with the η chain. CD3 is part of a bigger complex which includes the T Cell Receptor (TCR). This complex is expressed by mature T cells and by thymocytes. T cell activation may be induced when a foreign antigen is presented to the TCR through MHC complex.

Caractéristiques

Target Species Human
Specificity CD3
Other Names CD3
Fluorochrome UNLB
Regulatory Status ASR
Size 0.2 mg / 0.2 mg
Format Freeze-dried
Clone UCHT1
Isotype IgG1 Mouse
Clone Description UCHT1 reacts with the ε-chain of the CD3 complex. It was used as a CD3 reference mAb (ref.6T-CD3.1) during HLDA 6. After permeabilization with saponin-based permeabilization reagent IntraPrep, it may be used to detect intracytoplasmic CD3 by flow cytometry.

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