CD54-FITC

IM0726U

List Price - 320.70


The CD54 antigen, previously known as ICAM-1 (InterCellular Adhesion Molecule-1), is a 90 kDa transmembrane glycoprotein. With seven potential N-linked glycosylation sites, its structure, as that of CD50 (ICAM-3) and CD102 (ICAM-2), is related to the Immunoglobulin family. The CD54 antigen mediates the adhesion of T lymphocytes with Antigen-Presenting Cells (APC) and is involved in T cell to T cell and T cell to B cell interactions. It is also involved in the adhesion of monocytes, lymphocytes and neutrophils to activated endothelium. It binds to the integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It is a receptor for the rhinovirus. It is expressed by endothelial cells and by many other cell types upon activation.

Caractéristiques

Target Species Human
Specificity CD54
Other Names CD54, ICAM-1, intercellular adhesion molecule 1
Fluorochrome FITC
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone 84H10
Isotype IgG1 Mouse
Clone Description 84H10 antibody inhibits ICAM-1 mediated adhesion to LFA-1.
Cross Reactivity Canine

Customers Also Viewed

TOUS LES PRODUITS NE SONT PAS DISPONIBLES DANS TOUS LES PAYS
LA DISPONIBILITE DU PRODUIT ET LE STATUT REGLEMENTAIRE DEPENDENT DE L’ENREGISTREMENT SELON LE REGLEMENT APPLICABLE PAR PAYS