CD58-FITC

IM1218U

List Price - 390.80


CD58 is a glycoprotein of 65-70 kDa, either transmembrane or glycosylphosphatidylinositol (GPI)-anchored. CD58 was first described as the lymphocyte-function associated antigen 3 (LFA-3). LFA-3 was further shown to interact with CD2 suggesting an important role in various immunological responses via T-cell adhesion and activation. CD58 mediates adhesion between killer and target cells, antigen presenting cells and T cells. This antigen is widely expressed on leucocytes, erythrocytes and endothelial cells.

Caractéristiques

Target Species Human
Specificity CD58
Other Names CD58, LFA-3, lymphocyte function associated antigen-3
Fluorochrome FITC
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone AICD58
Isotype IgG2a Mouse
Clone Description The AICD58 antibody is a blocking antibody in LFA-3 mediated adhesion. This antibody was used as a CD58 reference mAb during HLDA 6.

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