CD62L-PB Conjugated Antibody

B30640

List Price - 375.60


The CD62L antigen, also called LECAM-1, L-selectin or LAM-1, is a 75 kDa molecule. It acts as the peripheral lymph node homing receptor. It is also involved in lymphocyte binding to High Endothelial Venules (HEV) and in lymphocyte rolling on activated endothelium. CD62L is expressed by B and T lymphocytes, monocytes, neutrophils, eosinophils, and approximately half of the peripheral NK lymphocytes. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.

Caractéristiques

Target Species Human
Specificity CD62L
Other Names CD62L, LAM-1, LECAM-1, L-selectin
Fluorochrome Pacific Blue*
Regulatory Status ASR
Size 0.5 mL
Format Liquid
Flow Product Line IOTest
Clone DREG56
Isotype IgG1 Mouse
Clone Description In contrast to other antibodies recognizing this molecule, DREG56 is particularly effective in blocking CD62L mediated lymphocyte binding to lymph node HEV. DREG56 (ref.33) was used as a CD62L reference monoclonal antibody during the HLDA 6.
Cross Reactivity Bovine, Chimpanzee

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