CD83-PE

IM2218U

List Price - 529.70


CD83, or HB15 molecule, is a 43 kDa glycoprotein member of the immunoglobulin superfamily. It is composed of a single extracellular V-type Ig-like domain, a transmembrane region and a 40 amino acid cytoplasmic domain. CD83 is predominantly expressed by dendritic lineage cells including Langerhans cells, skin and peripheral blood dendritic cells. It is also expressed by interdigitating reticulum cells present in the T cell zones of lymphoid organs as well as being weakly expressed by some germinal center lymphocytes. CD83 is expressed by in vitro generated dendritic cells. It is not expressed by resting peripheral blood leucocytes at detectable levels and is only expressed at low levels following lymphocyte activation in vitro.

Caractéristiques

Target Species Human
Specificity CD83
Other Names CD83, HB15
Fluorochrome PE
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone HB15a
Isotype IgG2b Mouse
Cross Reactivity Indian Rhesus, Common Marmoset, Squirrel Monkey

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